Well, I have been avoiding submitting one of my stories (Liz & Pip), though it is a personal favorite, as I have not been able to figure out a suitable layout for creating a dummy. What does this mean? Well, I have finally admitted to myself that the whole illustrative concept will have to change. To get a sense of what I have gone through on this project, this has been my journey:
1. Story idea comes to me! I write the whole thing in 5 minutes. Made a couple of small edits a few years later.
2. Begin illustrating. Complete about half of the book as a combination of collage and watercolour. The pages look pretty dull as there isn't much 'action' in the story, and I feared for rights management in the images I had appropriated. I put it away for awhile.
3. The whole batch vanishes from my parents home. (Likely thrown out.)
4. Decide to begin developing layout - and start with little illustrated drop caps. Love them so much and it brings the necessary 'action' to the pages - begin illustrating the whole thing in giant illuminated letters. Have completed the book mostly with about 46 pages of ridiculously detailed drawings.
here is a sample 
5. Very happy with most of the letters - however can't get a book layout to work. Put it away again for awhile. Did some submissions - but I wasn't quite happy with it yet.
6. Realized I must redo the whole thing. But I think I can salvage some of the letters and still use a few of them. I also think that the process of creating the last set gave me a way to make the book work. In other words, I won't lose all my work, I have a ton of my own reference material now - however, I will need to redraw it completely differently. I am actually looking forward to that now.
All in all, 10 years of work...but this time, I will get it right.